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Three ditopic-abiotic receptors ( R1 , R2 and R3 ) have been designed and synthesised. The receptors have been applied for the recognition of dicarboxylic acids viz. malonic, succinic, glutaric and adipic acids. Among them, succinic acid shows the highest binding efficiency to all receptors. Recognition of succinic acid is very important due to its various adverse effects on human health upon prolonged exposure.
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Dey et al. (2014) studied this question.
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