Key result
EuroSCORE II outperforms the GERAADA score in predicting acute type A aortic dissection operative mortality.
Why the study?
The predictive accuracy of the GERAADA score and EuroSCORE II for 30-day mortality after acute type A aortic dissection surgery required validation.
Does the EuroSCORE II model predict operative mortality better than the GERAADA score in patients undergoing surgery for acute type A aortic dissection?
Observational (n=147)
No
Does the EuroSCORE II model predict operative mortality better than the GERAADA score in patients undergoing surgery for acute type A aortic dissection?
The EuroSCORE II provides better discriminative power than the GERAADA score for predicting operative mortality in patients undergoing surgery for acute type A aortic dissection.
Answers are grounded in this paper and cite their sources.
May support EuroSCORE II over GERAADA for operative risk stratification in acute type A aortic dissection; leaves open prospective validation before practice change.
OBJECTIVES: The German Registry of Acute Aortic Dissection Type A (GERAADA) on-line score calculator to predict 30-day mortality in patients undergoing surgery for acute type A aortic dissection (ATAAD) was recently launched. Using the European System for Cardiac Operative Risk Evaluation II (EuroSCORE II), it is also possible to predict operative mortality for the same type of surgery. The goal of our study was to validate the prediction accuracy of these 2 on-line risk prediction models. METHODS: Prospectively collected data for EuroSCORE II risk factors as well as all data for GERAADA scoring were extracted from an institutional database for 147 patients who underwent surgery for ATAAD between April 2018 and April 2021. The discriminative power was assessed using area under the receiver operating characteristic curve. The calibration of the models was tested by the Hosmer-Lemeshow statistics and by using the observed-to-expected (O/E) mortality ratio with the 95% confidence interval. RESULTS: The observed operative mortality was 14.3%. The mean predicted mortality rates for the GERAADA score and the EuroSCORE II were 15.6% and 10.6%, respectively. The EuroSCORE II discriminative power (area under the curve = 0.799) significantly outperformed the discriminatory power of the GERAADA score (area under the curve = 0.550). The Hosmer-Lemeshow statistics confirmed good calibration for both models (P-values of 0.49 and 0.29 for the GERAADA score and the EuroSCORE II, respectively). The O/E mortality ratio certified good calibration for both scores [GERAADA score (O/E ratio of 0.93, 95% confidence interval: 0.53-1.33); EuroSCORE II (O/E ratio of 1.35, 95% confidence interval: 0.77-1.93)]. CONCLUSIONS: The EuroSCORE II has better discriminative power for predicting operative mortality in ATAAD surgery than the GERAADA score. Both scores confirmed good calibration ability.
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Nežić et al. (2021) conducted an observational in Acute type A aortic dissection (ATAAD) (n=147). EuroSCORE II vs. GERAADA score was evaluated on Discriminative power (AUC) for operative mortality. EuroSCORE II demonstrated significantly better discriminative power (AUC 0.799) than the GERAADA score (AUC 0.550) for predicting operative mortality in acute type A aortic dissection surgery.
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