Footprints of a metal: The uranyl ion (UO22+) binds to selected proteins, at specific sites, with high affinities. This property was exploited to photocleave proteins at the UO22+-binding site. Quenching studies show that free UO22+ is not responsible for the cleavage. This is the first report of protein photocleavage with high selectivity by the uranyl ion, upon excitation with visible light.
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Duff et al. (2005) studied this question.
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