Key result
Epicardial potassium chloride in dogs depresses baseline, TP, and PR segments, leaving ST take-off isoelectric.
Why the study?
A technique was developed to yield consistently reproducible electrocardiographic records of injury effects in dogs after epicardial application of potassium chloride.
Does the application of potassium chloride to the epicardium cause specific electrocardiographic injury effects in dogs?
Population
Dogs subjected to epicardial potassium chloride application
Comparison
Electrocardiograms recorded by string galvanometer vs condenser coupled amplifier
Design
Preclinical experimental study
Authors
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Distinguishes baseline/TP/PR depression from ST elevation in canine epicardial injury; extends experimental ECG data but leaves human relevance open.
Does the application of potassium chloride to the epicardium cause specific electrocardiographic injury effects in dogs?
Epicardial injury from potassium chloride in dogs causes depression of the baseline, TP, and PR segments without altering the ST segment take-off level.
Donoso et al. (1957) studied epicardial injury. application of potassium chloride to the epicardium was evaluated on electrocardiographic records of injury effects. Application of potassium chloride to the epicardium in dogs resulted solely in a depression of the baseline, TP, and PR interval segments, with the ST segment take-off remaining isoelectric.
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