Postbiotics: A promising frontier in improving periodontal disease

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Periodontal disease is a prevalent condition in oral medicine with a complex pathogenesis. While advancements in technology have led to progressive refinement in treatment methods for periodontal disease, postbiotics, which are novel derivatives of probiotics, have shown significant potential in assisting in the treatment of periodontal disease due to their unique antibacterial and anti-inflammatory properties. While many studies have explored postbiotics for periodontal disease adjunctive treatment, exactly how they work is still not fully understood. This article summarizes recent experimental, clinical, and practical research on the adjunctive treatment of periodontal disease with postbiotics, including their potential mechanisms, to provide insights for future clinical applications and the development of related functional foods.