Key result
High-voltage QRS complexes lack specificity for LVH, appearing in ~39% of patients without cardiac disease.
Why the study?
The lack of specificity of voltage changes in the Sokolow and Lyon criteria limits their clinical application for diagnosing left ventricular hypertrophy.
Do Sokolow-Lyon voltage criteria for left ventricular hypertrophy accurately predict clinical cardiac disease in patients with otherwise normal electrocardiograms?
Population
Unselected group of patients with otherwise normal electrocardiograms showing high-voltage QRS complexes
Comparison
Voltage criteria for left ventricular hypertrophy by Sokolow and Lyon vs clinical evidence of cardiac disease
Design
Observational study
Authors
Loading...
Voltage criteria alone lack specificity and should not yet change practice; supports validation of combined abnormalities in prospective cohorts.
Observational
Do Sokolow-Lyon voltage criteria for left ventricular hypertrophy accurately predict clinical cardiac disease in patients with otherwise normal electrocardiograms?
High-voltage QRS complexes alone lack specificity for clinical cardiac disease, limiting the clinical application of Sokolow-Lyon voltage criteria for left ventricular hypertrophy.
Cumming et al. (1959) conducted an observational in Left Ventricular Hypertrophy. High-voltage QRS complexes was evaluated on Absence of clinical evidence of cardiac disease. High-voltage QRS complexes lacked specificity for left ventricular hypertrophy, as 39% of ECGs meeting precordial criteria and 29% meeting aVL criteria occurred in patients without cardiac disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: