A new effective method has been elaborated for the preparation of the hitherto unknown C-3 halogene derivatives (Cl, Br) of apocodeine and apomorphine, as well as of their N-demethyl-N-substituted (N-propyl, N-alkyl) analogues. These compounds are expected to possess an effect on the dopamine receptor system.
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Simon et al. (1991) studied this question.
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