Microsporidiosis has been implicated in causing morbidity in immune-compromised and immune-competent individuals. As microsporidiosis is acquired via an oral route, gut-associated lymphoid tissues have been found to be critical for the initial control of this infection. Studies from our laboratories have demonstrated that IELs play a dominant role in this protection; however, the mechanisms involved in the trafficking of these cells and their role in long-term immunity remain to be elucidated.
No takes yet. Share an insight, caveat, or question.
Moretto et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: