Key result
Uncomplicated MVP linked to silent cerebral infarcts, detected by MRI in ~10% of patients.
Why the study?
It is unclear whether uncomplicated mitral valve prolapse is a risk factor for silent cerebral ischemic events.
Is uncomplicated mitral valve prolapse a risk factor for silent cerebral infarcts?
Comparison
Uncomplicated MVP vs control subjects without MVP
Design
Observational study
Authors
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Should not yet change MVP management or prompt routine MRI; leaves open causality and need for prospective confirmation.
Observational (n=98)
Is uncomplicated mitral valve prolapse a risk factor for silent cerebral infarcts?
Uncomplicated mitral valve prolapse may be associated with an increased risk of silent cerebral infarcts, suggesting a potential role for antiplatelet therapy in these patients.
Topçu et al. (2005) conducted an observational in Mitral valve prolapse (n=98). Uncomplicated mitral valve prolapse vs. Subjects without mitral valve prolapse was evaluated on Silent cerebral infarct (SCI). Uncomplicated mitral valve prolapse was identified as a risk factor for silent cerebral infarcts, which were detected by MRI in 9.6% of MVP patients.
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