Key result
Preoperative interatrial block linked to ~164% greater risk of postoperative atrial fibrillation.
Why the study?
Atrial fibrillation is a common complication after heart surgery, and the relationship between preoperative interatrial block and postoperative atrial fibrillation was unclear.
Is preoperative interatrial block associated with an increased risk of postoperative atrial fibrillation in patients undergoing cardiac surgery?
Cohort (n=1,350)
Is preoperative interatrial block associated with an increased risk of postoperative atrial fibrillation in patients undergoing cardiac surgery?
Preoperative interatrial block is a strong independent predictor of postoperative atrial fibrillation after cardiac surgery, suggesting its utility in preoperative risk stratification.
May aid preoperative AF risk stratification on ECG; leaves open whether targeted interventions improve outcomes.
OBJECTIVES: Atrial fibrillation is a common complication after heart surgery, potentially leading to chronic atrial fibrillation, heart failure and mortality. The aim of this study was to explore the relationship between preoperative interatrial block and the occurrence of postoperative atrial fibrillation. METHODS: Perioperative 12-channel electrocardiographies of patients in sinus rhythm scheduled for heart surgery, including bypass and/or valve surgery, were analysed. Patients with pre-existing atrial fibrillation, amiodarone therapy, atrioventricular block II or III, or pacemaker were excluded from the study. Clinical parameters in patients with versus without atrial fibrillation were compared. To evaluate the association between interatrial block and postoperative atrial fibrillation, univariable and multivariable regression analyses were performed. RESULTS: Out of 2374 patients, 1350 were amenable to analysis. Postoperative atrial fibrillation was documented in 505 (37.4%) patients. In multivariable regression analysis, prediction models with and without interatrial block were established. Step-wise regression analysis identified interatrial block [2.64 (2.02; 3.46), P < 0.001), age [1.11 (1.03; 1.20), P = 0.007], EuroScore II [1.05 (1.03; 1.07), P < 0.001], pulmonary hypertension [1.91 (1.24; 2.97), P = 0.006], history of cardiogenic shock [2.05 (1.11; 3.87), P = 0.032], statins [1.66 (1.21; 2.27), P = 0.002], chronic obstructive pulmonary disease [2.11 (1.25; 3.65), P = 0.009] and cardiopulmonary bypass time [1.78 (1.04; 3.05), P = 0.047] as independent predictors for postoperative atrial fibrillation. CONCLUSIONS: Preoperative interatrial block was associated with a higher incidence of postoperative atrial fibrillation. Inclusion of electrocardiography-derived preoperative conduction disturbances can enhance risk stratification of postoperative atrial fibrillation after heart surgery.
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Leiler et al. (2024) conducted a cohort in Patients scheduled for heart surgery (n=1,350). Preoperative interatrial block vs. No preoperative interatrial block was evaluated on Postoperative atrial fibrillation (OR 2.64, 95% CI 2.02-3.46, p=<0.001). Preoperative interatrial block was independently associated with a higher incidence of postoperative atrial fibrillation after heart surgery (OR 2.64; 95% CI 2.02-3.46; P<0.001).
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