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March 30, 2009European Journal of Cardio-Thoracic Surgery

Preoperative atrial fibrillation decreases event-free survival following cardiac surgery☆

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Why the study?

Does preoperative atrial fibrillation decrease event-free survival in patients undergoing coronary artery bypass graft and/or valve surgery?

Population

9,796 consecutive patients undergoing coronary artery bypass graft and/or valve surgery between 1995 and…

Comparison

Preoperative atrial fibrillation (exposure) vs No preoperative atrial fibrillation

Design

Cohort

Follow-up

Median 2.9 years (maximum 11 years)

Authors

DKDimitri KalavrouziotisLung InstituteKBKaren J. ButhDalhousie UniversityTVTarren VyasDalhousie University

Discussion

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Implication

Preoperative AF signals higher long-term risk after CABG or valve surgery; leaves open whether targeted rhythm interventions improve outcomes.

Structured PICO

Does preoperative atrial fibrillation decrease event-free survival in patients undergoing coronary artery bypass graft and/or valve surgery?

P
Population
9,796 consecutive patients undergoing coronary artery bypass graft (CABG) and/or valve surgery between 1995 and 2005, with no concomitant surgical atrial fibrillation ablation.
I
Intervention
Preoperative atrial fibrillation (exposure)
C
Comparator
No preoperative atrial fibrillation
O
Outcome
Event-free survival (composite of late death and cardiovascular-related re-hospitalization) at median 2.9 years follow-upcomposite

Preoperative atrial fibrillation is a significant independent predictor of decreased long-term event-free survival following CABG or valve surgery.

Cite This Study

Kalavrouziotis et al. (2009) studied this question.

synapsesocial.com/papers/6a76bca31400807f0f1e63d0https://doi.org/10.1016/j.ejcts.2009.02.030

Topics

Atrial fibrillationPersistent AF managementValvular heart diseaseAnticoagulation in AFAF ablation outcomes
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation)2019 · 43 citations
  2. 2Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications1995 · 2,287 citations
  3. 3The impact of diffuseness of coronary artery disease on the outcomes of patients undergoing primary and reoperative coronary artery bypass grafting☆2007 · 28 citations
  4. 4Comparison of 2 Methods for Calculating Adjusted Survival Curves From Proportional Hazards Models2001 · 254 citations
  5. 5Relationships Between Sinus Rhythm, Treatment, and Survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study2004 · 1,219 citations