What question did this study set out to answer?

To determine whether continuous transcutaneous carbon dioxide partial pressure monitoring can accurately predict when arterial carbon dioxide reaches the 60 mmHg diagnostic threshold during apnea testing.

March 28, 2006AnesthesiologyOpen Access

An Evaluation of Transcutaneous Carbon Dioxide Partial Pressure Monitoring during Apnea Testing in Brain-dead Patients

View Full Paper

Ask AI

Bookmark

To determine whether continuous transcutaneous carbon dioxide partial pressure monitoring can accurately predict when arterial carbon dioxide reaches the 60 mmHg diagnostic threshold during apnea testing.
Monitored 32 clinically brain-dead patients using a transcutaneous ear sensor alongside arterial blood gas measurements during apnea testing.
Identified the optimal transcutaneous cutoff value using receiver operating characteristic curve analysis in an initial cohort of 20 patients.
Applied the identified 60 mmHg transcutaneous threshold to guide test termination in a subsequent cohort of 12 patients.
In the first 20 patients, a transcutaneous threshold of 60 mmHg predicted an arterial carbon dioxide of 60 mmHg with an area under the curve of 0.983 +/- 0.013 and a positive predictive value of 1.00 (95% CI, 0.93-1.00).
Using the 60 mmHg transcutaneous target reduced mean apnea test duration (11 +/- 4 vs. 20 +/- 0 min; P < 0.001), peak hypercapnia (74.0 +/- 4.9 vs. 98.3 +/- 20.0 mmHg; P < 0.001), and severe acidosis (pH 7.18 +/- 0.06 vs. 7.11 +/- 0.08; P < 0.001).
Patients managed with transcutaneous monitoring experienced a significantly smaller decrease in arterial oxygen partial pressure (-47 +/- 44 vs. -95 +/- 89 mmHg; P < 0.05) compared to the standard 20-minute group.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Comparative study reveals transcutaneous carbon dioxide monitoring accurately predicts arterial targets during apnea testing, indicating test duration and complications can be reduced.

Cite This Study

Vivien et al. (2006) studied this question.

synapsesocial.com/papers/6aaf543f2222a12e8bd06702 https://doi.org/10.1097/00000542-200604000-00014

View Full Paper

Ask AI

Bookmark

Implication

Comparative study reveals transcutaneous carbon dioxide monitoring accurately predicts arterial targets during apnea testing, indicating test duration and complications can be reduced.

An Evaluation of Transcutaneous Carbon Dioxide Partial Pressure Monitoring during Apnea Testing in Brain-dead Patients

Key Points

Discussion

Implication

Cite This Study

An Evaluation of Transcutaneous Carbon Dioxide Partial Pressure Monitoring during Apnea Testing in Brain-dead Patients

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider