Key result
Normal sex differences in digital skin temperature and DBI disappear in primary Raynaud's phenomenon.
Why the study?
Objective assessment of vasospastic ischemic disease in primary Raynaud's phenomenon patients was needed to address variability and sex differences in measurements.
Can digital systolic blood pressure and skin temperature measurements before and after cold provocation differentiate patients with primary Raynaud's phenomenon from healthy volunteers?
Cross-Sectional (n=62)
Can digital systolic blood pressure and skin temperature measurements before and after cold provocation differentiate patients with primary Raynaud's phenomenon from healthy volunteers?
Sex differentiation is essential for the objective assessment of primary Raynaud's phenomenon using digital pressure and temperature measurements, as healthy females show similar results to patients.
May support sex-specific norms for digital perfusion testing in healthy adults; leaves open relevance in primary Raynaud's phenomenon.
In order to assess vasospastic ischemic disease objectively 41 patients with primary Raynaud's phenomenon and 21 normal volunteers were investigated noninvasively by digital systolic blood pressure and digital skin temperature measurements before and after instant cold provocation. Much care had been taken to be certain that all patients had primary Raynaud's phenomenon. The results of digital pressure measurements appeared to be affected by interindividual variations in systemic systolic blood pressure. By introducing a digit-to-brachial systolic blood pressure index (DBI), such variations could be eliminated. Instant cold provocation did not change DBI significantly. No pressure drop due to a closing phenomenon could be observed. Both digital skin temperature and DBI differed significantly between healthy males and females. In the patient group males and females did not show significant differences. The results in healthy females were hardly different from the results in patients. Healthy males could be well discriminated from patients with both techniques. Sex differentiation appeared to be essential for the objective assessment of primary Raynaud's phenomenon.
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Wal et al. (1987) conducted a cross-sectional in Primary Raynaud's phenomenon (n=62). Primary Raynaud's phenomenon vs. Normal volunteers was evaluated on Digital systolic blood pressure (digit-to-brachial systolic blood pressure index) and digital skin temperature before and after instant cold provocation. Digital skin temperature and digit-to-brachial systolic blood pressure index differed significantly between healthy males and females, but not between male and female patients with primary Raynaud's phenomenon.
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