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All articles of this category Racemic ethyl threo -3-(4-methylthiophenyl)serinate is resolved by enzymatic hydrolysis using protease from Streptomyces griseus and both stereoisomers are converted to D- threo -4, 5-dihydro-5-(4-methylsulfonylphenyl)-2-phenyl-4-oxazolemethanol, thereby giving a formal synthesis of florfenicol.
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Clark et al. (1991) studied this question.
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