A case of keratitis, ichthyosis, and deafness syndrome with rickets

Keratitis, ichthyosis, deafness (KID) syndrome is a rare disorder of cornification and a distinct type of congenital ichthyosis with predominantly autosomal dominant inheritance. The classical triad is keratitis, progressive erythrokeratoderma, and hearing loss.1,2 KID syndrome is a result of missense mutation in the GJB2 (gap junction β2) gene on chromosome 13q11-q12, which encodes connexin 26 protein. This protein is involved in formation of intercellular channels and has a role in epithelial differentiation.