Key result
Outpatient phenprocoumon links to ~12 bleeds per 100 treatment-years, mostly managed with vitamin K.
Why the study?
Management strategies for bleeding complications in patients on oral anticoagulation require clarification regarding optimal antagonization approaches and outcomes.
Cohort (n=45)
No
In a small cohort of outpatients on phenprocoumon, bleeding complications were mostly minor and effectively managed with dose reduction and vitamin K.
No takes yet. Share an insight, caveat, or question.
Bleeding rates with phenprocoumon warrant ongoing outpatient vigilance; leaves open need for larger prospective studies on real-world incidence.
Pindur et al. (1999) conducted a cohort in Oral anticoagulation therapy (n=45). Phenprocoumon was evaluated on Bleeding complications. Among 45 out-patients receiving phenprocoumon over 2 years, there were 11 bleeding complications (11.6 per 100 treatment-years), mostly managed by discontinuing treatment and vitamin K.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: