Why the study?
Nonalcoholic fatty liver disease is the most common liver disease in China, necessitating updated evidence-based practical recommendations for diagnosis and treatment.
Provides updated expert consensus recommendations for the standardized diagnosis and management of NAFLD in China.
Answers are grounded in this paper and cite their sources.
May guide NAFLD care in China; leaves open need for RCTs to validate recommendations.
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in China. To provide evidence-based and updated practical recommendations for clinician, this expert recommendations have updated the diagnosis and treatment of NAFLD in five aspects as follows: (1) the framework of NAFLD treatment centre or clinic; (2) screening and evaluation: who should be screened, initial evaluation items, non-invasive assessment of steatohepatitis and advanced fibrosis, when to obtain a liver biopsy in patients with NAFLD, and other metabolic disorders and cardiovascular risk assessment; (3) managements of patient with NAFLD: lifestyle intervention (dietary, exercise and weight loss), drug treating metabolic co-morbidities such as hyperlipidemia, type 2 diabetes mellitus and hypertension, and steatohepatitis and fibrosis; (4) management of special populations with NAFLD: children, pregnant or lactating women, patients co-existence with alcoholic liver disease, chronic HBV and/or HCV infection, and autoimmune disorders; (5) monitoring and follow-up. This consensus aims to modify the optimizing management process and guide physicians make correct and reasonable decisions in the diagnosis and treatment for patients with NAFLD.
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A 2019 study conducted a review in Nonalcoholic fatty liver disease (NAFLD). Expert recommendations on standardized diagnosis and treatment was evaluated. Updated expert recommendations provide a comprehensive framework for the screening, evaluation, lifestyle and pharmacological management, and follow-up of patients with NAFLD in China.
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