Key result
Dexmedetomidine plus ropivacaine is linked to ~61 minutes longer sensory block versus ropivacaine alone.
Why the study?
The effects of dexmedetomidine combined with local anesthetics in brachial plexus block evaluated by ultrasound imaging using global joint entropy algorithm were explored.
Does dexmedetomidine combined with ropivacaine prolong sensory and motor block and reduce postoperative pain in patients undergoing upper limb surgery with brachial plexus block?
Does dexmedetomidine combined with ropivacaine prolong sensory and motor block and reduce postoperative pain in patients undergoing upper limb surgery with brachial plexus block?
Dexmedetomidine combined with local anesthetics prolongs the duration of sensory and motor nerve block and reduces postoperative pain in patients undergoing upper limb surgery.
Answers are grounded in this paper and cite their sources.
Should not yet alter brachial plexus block practice; leaves open adjunctive role pending randomized confirmation.
This paper aimed to explore dexmedetomidine combined local anesthetics in brachial plexus block through ultrasound imaging (UI) under global joint entropy algorithm. Patients who underwent upper limb surgery and brachial plexus block were selected as research objects. Patients in group A were given 0.375% ropivacaine and normal saline, and patients in group B were given 0.375% ropivacaine and 1.0 μg/kg dexmedetomidine. The results of UI were analyzed by global joint entropy-based K-means clustering (GKC) algorithm, and the use effects of the two methods were compared in combination with other postanesthesia manifestations. The results were as follows. The segmentation accuracy (96.21% and 83.52%) of GKC was higher than 82.21% and 70.52% of the local joint entropy-based K-means clustering (LKC) ( P < 0.05 ). The duration of sensory and motor block (352.78 ± 45.89 min and 324.38 ± 41.29 min) in group B was significantly longer than 292.28 ± 35.69 min and 256.58 ± 42.76 min in group A ( P < 0.05 ). Compared with 84.91 ± 8.77 beats/min and 89.58 ± 7.62 beats/min in group A, mean arterial pressure (70.24 ± 9.77 beats/min and 69.89 ± 8.97 beats/min) in group B was lower at T1 and T2 ( P < 0.05 ). The duration of postoperative pain (582.70 ± 51.89 min) in group B was longer than 372.89 ± 49.89 min in group A ( P < 0.05 ). The postoperative pain score (2.98 ± 1.08) in group B was significantly lower than 4.48 ± 2.19 in group A ( P < 0.05 ). Therefore, dexmedetomidine combined local anesthetics could prolong the duration of sensory and motor nerve block. Besides, dexmedetomidine had sedative and analgesic effects, so as to prolong postoperative pain time and reduce pain degree of patients.
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Ge et al. (2021) studied Upper limb surgery requiring brachial plexus block. Dexmedetomidine combined with ropivacaine vs. Normal saline and 0.375% ropivacaine was evaluated on Duration of sensory block (p=< 0.05). Dexmedetomidine combined with ropivacaine significantly prolonged the duration of sensory block (352.78 vs 292.28 min) and motor block (324.38 vs 256.58 min) compared to ropivacaine alone (P<0.05).
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