Key result
Obesity and insulin resistance promote atherothrombosis via mechanisms requiring strategies to overcome antiplatelet drug resistance.
Why the study?
Pathogenetic mechanisms of cardiovascular disease development in obesity and insulin resistance and approaches to prevent atherothrombotic complications require synthesis and evaluation.
This review discusses the pathogenetic mechanisms of cardiovascular disease in obesity and insulin resistance, focusing on atherothrombosis and overcoming antiplatelet drug resistance.
Answers are grounded in this paper and cite their sources.
May warrant attention to antiplatelet resistance in obese insulin-resistant patients; leaves open optimal atherothrombotic prevention strategies.
Article takes into consideration pathogenetic mechanisms of cardiovascular diseases development in obesity and insulin resistance, approaches to atherothrombotic complications prevention. The issues of resistance to antiplatelet drugs are condsidered and possible ways for its overcome. The data is evidence based.
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V. N. Shishkova (2016) studied this question. Obesity and insulin resistance promote cardiovascular disease and atherothrombosis through pathogenetic mechanisms that necessitate strategies to overcome antiplatelet drug resistance.
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