Key result
Marathon running in master runners shows no link to myocardial injury or elevated troponin.
Why the study?
The short-term effects of marathon running on serum cardiac markers in master runners over 60 years old were not well characterized.
Does marathon running cause acute myocardial injury as measured by cardiac biomarkers in master runners over 60 years old?
Observational (n=10)
Does marathon running cause acute myocardial injury as measured by cardiac biomarkers in master runners over 60 years old?
Marathon running does not appear to cause acute myocardial injury in elderly master runners, as evidenced by normal post-race cardiac troponin I levels.
Marathon running did not raise troponin I in masters athletes; hypothesis-generating and should not yet change practice or guidelines.
The purpose of this investigation was to analyze the short-term effects of marathon running on serum levels of cardiac markers in a group of master runners (> 60 yrs). Ten marathoners (9 male and 1 female; 63+/-4 yrs) were enrolled in the study. All of them completed the Madrid Marathon (1998). Venous blood was drawn from each subject three times during the study (48 h before the race, immediately after the race, and 24 h post-competition) for the determination of the several biochemical markers, such as total creatine kinase catalytic activity (total CK), mass concentration of creatine kinase isoenzyme MB (CK-MB mass), and cardiac troponin I (Tnl-c). The most important finding was that in each sample (pre- or post-race) serum Tnl-c was below the commonly accepted level of 0.1 ng x m(-1) indicative of myocardial injury. Although further research is needed using more complete methodology, our results suggest that marathon running does not have an acute deleterious effect on the hearts of the elderly.
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Lucía et al. (1999) reported an observational. Marathon running vs. Pre-race baseline was evaluated on Serum cardiac troponin I (cTnI) levels. Marathon running in master runners did not cause myocardial injury, with serum cardiac troponin I remaining below the 0.1 ng/ml threshold in all pre- and post-race samples.
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