Evaluation of Cell Lines for the Isolation of Foot-and-Mouth Disease Virus and Other Viruses Causing Vesicular Disease

Figures

• 

  Figure 1. Titers of FMDV A/IRN/24/2012 epithelium suspension tested on BTY, IB-RS-2, ZZ-R 127, and LFBK-αVβ6 cells. The lines represent the trend of titers over time. No trendline is present for BTY cells as these are independent, weekly batches.

• 

  Figure 2. Titers of FMDV O/KUW/4/2016 epithelium suspension tested on BTY, IB-RS-2, ZZ-R 127, and LFBK-αVβ6. The lines represent the trend of titers over time. No trendline is present for BTY cells as these are independent, weekly batches.

• 

  Figure 3. Titers of SVDV/UKG/77/80 epithelium suspension tested on IB-RS-2 and LFBK-αVβ6. The lines represent the trend of titers over time.

• 

  Figure 4. Titers of epithelium suspensions tested on primary BTY cells and ZZ-R 127 cells. Samples are color coded based on FMDV serotype as follows: O, A, SAT 1, SAT 2, and Asia 1. The dotted green line indicates where the limit of detection was identical between the cells; samples with data points above the line indicate a lower limit of detection in ZZ-R 127 and samples with data points below the line indicate a lower limit of detection in BTY cells.

• 

  Figure 5. Titers of epithelium suspensions tested on primary BTY cells and LFBK-αvβ6 cells. Samples are color coded based on FMDV serotype as follows: O, A, SAT 1, SAT 2, and Asia 1. The dotted green line indicates where the limit of detection was identical between the cells; samples with data points above the line indicate a lower limit of detection in LFBK-αvβ6 and samples with data points below the line indicate a lower limit of detection in BTY cells.