Wet Chemical Processing of Pure and Nickel Substituted Hydroxyapatite and Its Characterization for Bio-Medical Applications

Hydroxyapatite (HAp) is a calcium phosphate that resembles the hard tissues of humans. It is the primary component of bone and enamel and can be produced artificially using a variety of techniques. Synthetic hydroxyapatite doped with metal ions might improve its various physiochemical and biological properties. The current study is based on a facile wet chemical technique for producing Ni substituted hydroxyapatite (HAp) nanoparticles with the processing conditions such as reaction temperature of 80°C, heat treatment temperature of 450°C and PH of 11. The influence of nickel on the structural, morphological and optical properties of the prepared samples was analyzed by XRD, SEM EDX, FTIR, and UV characterization techniques. Anti-bacterial behavior of the samples was analyzed by disc diffusion method. The results revealed that the prepared Ni-HAp particles had a flake-like morphology with a size of 60 nm. The FTIR spectra exhibited the functional groups present in the samples. The UV studies showed that the Ni incorporated HAp sample had enhanced optical properties.