Key result
Severe hypotension during shock drives S-T segment displacement, while vigorous limb massage triggers functional VF.
Why the study?
Functional myocardial changes during severe hypotension due to reduced coronary blood flow and their relation to circulatory failure and cardiac death after hemorrhage and ischemic compression shock were not fully understood.
Population
Subjects undergoing hemorrhage and ischemic compression shock
Comparison
Hemorrhage and ischemic compression with and without limb massage
Design
Other study design
Authors
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Persistent ST changes may flag ongoing ischemia after hypotension; leaves open potassium toxicity and massage effects on experimental VF.
The study suggests that ischemic compression and subsequent massage of limbs release potassium-like toxic substances that cause severe electrocardiographic changes and ventricular fibrillation.
Izquieta et al. (1946) studied Hemorrhage and Ischemic Compression Shock. Hemorrhage and Ischemic Compression Shock was evaluated on Electrocardiographic changes (S-T segment displacement). Severe hypotension during hemorrhage and ischemic compression shock led to S-T segment displacement, and vigorous limb massage precipitated functional ventricular fibrillation.