Key result
PCOS linked to ~51% higher CVD risk in women across all age groups.
Why the study?
The risk of cardiovascular disease in women with polycystic ovary syndrome and the global incidence of PCOS-associated CVD were not well quantified.
Does polycystic ovary syndrome increase the risk of cardiovascular disease in women?
Population
Women with polycystic ovary syndrome
Comparison
Women with PCOS vs women without PCOS
Design
Meta-analysis across five databases
Authors
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May warrant intensified CVD prevention in women with PCOS; supports association but leaves causal inference and interventions open.
Meta-Analysis
Yes
Does polycystic ovary syndrome increase the risk of cardiovascular disease in women?
Relative Risk: 1.51 (95% CI 1.36–1.69)
Women with PCOS have a 1.5-fold increased risk of cardiovascular disease, highlighting the need for enhanced prevention and treatment strategies in this population.
Wan et al. (2024) conducted a meta-analysis in Polycystic ovary syndrome (PCOS). Polycystic ovary syndrome vs. Women without polycystic ovary syndrome was evaluated on Cardiovascular disease (CVD) (RR 1.51, 95% CI 1.36-1.69). Polycystic ovary syndrome was associated with a significantly increased risk of cardiovascular disease in women across all age groups (RR 1.51; 95% CI 1.36-1.69).
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