A dinuclear Zn(II) complex of N2δ,N2δ,N 2′δ,N2′δ-tetra kis(2-pyridylmethyl) derivative of cyclic peptide gramicidin S markedly accelerated the cleavage of the phosphodiester linkage of the RNA model substrate 2-hydroxypropyl p-nitrophenyl phosphate.
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Yamada et al. (2000) studied this question.
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