Systematic review finds moderate quality across discrete choice experiments evaluating atopic dermatitis treatment preferences, highlighting the need for improved study designs.
OBJECTIVES: This study systematically reviews relevant studies on the application of discrete choice experiment (DCE) in treatment preference selection for atopic dermatitis (AD), with the aim of providing reference for the future application of DCE in clinical practice. METHODS: Relevant studies were retrieved from PubMed, Web of Science, Embase, Cochrane Library, CINAHL, Medline, WanFang Data and CNKI databases. The search time restricted to the establishment of the database to 22 October 2025. Two researchers independently conducted literature screening, after which they extracted data, and carried out quality evaluation using the PREFS scoring criteria. RESULTS: A total of 13 studies were included, mainly from European and American countries. According to the PREFS scale, 8 studies were rated 4 points and 5 studies 3 points in quality assessment. The main data analysis model was random parameter Logit. CONCLUSIONS: The research on the application of DCE in assessing AD treatment preferences is still in the development stage, with room for further improvement regarding respondents. Future relevant studies should adhere to the experimental design principles of DCE, while attaching importance to result attributes, so as to provide more high-quality evidence for research on AD treatment preferences.
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