Key result
Acute bacterial myocarditis causes rapid death in a nonneutropenic child with ALL in remission.
Why the study?
Acute bacterial myocarditis in patients with malignancy is rarely reported, and rapid clinical deterioration in such cases is not well characterized.
Case Report (n=1)
Highlights a rare and rapidly fatal presentation of acute bacterial myocarditis in a nonneutropenic pediatric patient with leukemia in remission.
Answers are grounded in this paper and cite their sources.
Supports consideration of bacterial myocarditis in acute heart failure among pediatric leukemia patients in remission; hypothesis-generating for surveillance strategies.
The authors report a fatal case of acute bacterial myocarditis in a nonneutropenic child with acute lymphoblastic leukemia. She was admitted to the hospital with a urinary tract infection resulting from and remained persistently febrile despite resolution of the infection. On hospital day 4 signs of acute cardiac failure developed. Despite aggressive resuscitation measures, she died. Pathologic examination revealed the cause of death to be bacterial myocarditis. In addition, she was found to have a generalized decrease in her serum immunoglobulin levels. Acute bacterial myocarditis in patients with malignancy has been rarely reported. The rapid clinical deterioration and death in the patient in this report is particularly interesting.
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Scothorn et al. (2002) conducted a case report in Acute bacterial myocarditis in acute lymphoblastic leukemia (n=1). Acute bacterial myocarditis was evaluated on Death. A nonneutropenic child with acute lymphoblastic leukemia in remission experienced rapid clinical deterioration and death due to acute bacterial myocarditis.
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