Key result
Smartphone ECG detects QTc prolongation with 97% accuracy versus 12-lead ECG in methadone patients.
Why the study?
Availability of a convenient, less resource-intensive method of ECG monitoring for patients taking methadone is desirable due to resource demands of routine ECG monitoring recommendations.
Does a single-lead smartphone ECG accurately measure QT intervals compared to a standard 12-lead ECG in patients on maintenance methadone therapy?
Observational (n=115)
Does a single-lead smartphone ECG accurately measure QT intervals compared to a standard 12-lead ECG in patients on maintenance methadone therapy?
A handheld smartphone ECG provides accurate QT interval measurements and can reliably identify QTc prolongation in patients on methadone therapy, offering a convenient monitoring alternative.
Answers are grounded in this paper and cite their sources.
May support convenient QTc monitoring in methadone patients; leaves open need for prospective validation before routine adoption.
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Titus-Lay et al. (2021) conducted an observational in Maintenance methadone therapy (n=115). Handheld smartphone ECG (iECG) vs. 12-lead ECG was evaluated on QTc bias compared to 12-lead ECG (MD -0.14 ms, 95% CI -2.4 to 2.1). A handheld smartphone ECG demonstrated a QTc bias of -0.14 ms (95% CI -2.4 to 2.1) compared to a 12-lead ECG and identified QTc prolongation with 97% accuracy in patients on methadone therapy.
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