Key result
Hypertension is linked to ~680% higher odds of CKD among medical ward patients.
Why the study?
Chronic kidney disease is a major non-communicable disease with variable global prevalence and leading causes including diabetes and hypertension, but its burden and predictors in developing countries need characterization.
Cross-Sectional (n=450)
Odds Ratio: 7.8 (95% CI 4.1–14.9)
p-value: p=<0.05
The burden of CKD is high among medical inpatients in this developing country setting, with hypertension, nephrotoxic drugs, and recurrent UTIs being strong predictors.
Supports inpatient CKD screening in hypertension; leaves open whether targeting these factors improves outcomes in low-resource settings.
Chronic Kidney Disease (CKD) is being recognized as a global public health problem. It is a major non-communicable disease with the global prevalence varying between 10.5% and 13.1%. Diabetes and hypertension appear to be the leading causes of chronic kidney disease worldwide. An institution based cross-sectional study was undertaken from Oct 20, 2018 to Nov 20, 2019 G.C. Data was collected using a pre-tested questionnaire designed to meet the study objective. After describing variables, logistic regression was conducted to identify independent associated factors of CKD. Statistical significance was declared at P<0.05. Of the 450 studied patients, 260(57.8%) were males and more than half (54.2%) were between ages of 25 to 40 years. The prevalence of CKD among patients admitted to medical ward was 17.3% (95% CI 13 - 29.9) and 14.4% (95 % CI 6.2 – 12.3) by Cockcroft Gault and MDRD equations, respectively and majority (61.5%) of them were stage 5. Hypertension (AOR= 7.8 95%CI 4.1, 14.9), history of recurrent urinary tract infection (AOR= 3.5 95% CI 1.1, 7.3) and history of using nephrotoxic drugs (AOR=3.4 95% CI 2, 9.3) were significantly associated with CKD. The burden of CKD among patients in a medical inpatient unit was high and majority of the patients present late. Hypertension, use of nephrotoxic agents and recurrent urinary tract infections were found to be important predictors.
No takes yet. Share an insight, caveat, or question.
Weldetensae et al. (2022) conducted a cross-sectional in Chronic Kidney Disease (n=450). Hypertension vs. Absence of hypertension was evaluated on Chronic Kidney Disease (AOR 7.8, 95% CI 4.1-14.9, p=<0.05). Hypertension was strongly associated with chronic kidney disease among medical ward patients (AOR 7.8; 95% CI 4.1-14.9), along with recurrent urinary tract infections and nephrotoxic drug use.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: