Key result
Pleural biopsy yields higher tubercle bacilli detection than pleural fluid, and cytocentrifugation further improves sensitivity.
Why the study?
Tuberculous pleurisy is difficult to diagnose due to nonspecific presentation, paucibacillary effusion, and inefficiency of conventional laboratory methods.
Does pleural biopsy examination improve the detection rate of tubercle bacilli compared to pleural fluid examination in patients with undiagnosed exudative pleural effusion?
Population
50 patients with undiagnosed exudative pleural effusion
Comparison
Pleural biopsy specimens vs pleural fluid examination
Design
Cross-sectional study using thoracoscopy and multiple diagnostic methods
Authors
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Pleural biopsy specimens combined with histopathology and microbiological examination provide a higher diagnostic yield for tuberculous pleurisy than pleural fluid examination alone.
Cross-Sectional (n=50)
Does pleural biopsy examination improve the detection rate of tubercle bacilli compared to pleural fluid examination in patients with undiagnosed exudative pleural effusion?
Pleural biopsy specimens combined with histopathology and microbiological examination provide a higher diagnostic yield for tuberculous pleurisy than pleural fluid examination alone.
Amer et al. (2016) conducted a cross-sectional in Undiagnosed exudative pleural effusion (suspected tuberculous pleurisy) (n=50). Pleural biopsy specimen examination vs. Pleural fluid examination was evaluated on Detection rate of tubercle bacilli. Pleural biopsy specimens had a higher detection rate of tubercle bacilli than pleural fluid, and cytocentrifugation improved microscopic detection sensitivity for both.
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