Key result
Coronary revascularization lacks widespread adoption for ischemic heart failure as key clinical questions remain.
Why the study?
Coronary revascularisation has not been widely adopted to treat ischaemic heart failure, and important questions remain before it can be considered standard treatment.
Does coronary revascularisation improve ventricular function in patients with ischaemic heart failure?
Does coronary revascularisation improve ventricular function in patients with ischaemic heart failure?
Discusses the unresolved role of coronary revascularisation for improving ventricular function in patients with ischaemic heart failure.
Benefit of revascularisation on ventricular function in ischaemic HF remains unresolved; leaves open need for definitive RCTs.
The concept of myocardial hibernation was first proposed in the 1980s, and cardiologists and cardiac surgeons have become familiar with the possibility of improving ventricular function by restoring myocardial blood flow to dysfunctional but viable areas of myocardium subtended by a stenotic coronary artery. Despite this, coronary revascularisation has not been widely adopted as a strategy to treat patients with ischaemic heart failure. Indeed it seems likely that most cases of “ischaemic” heart failure are never investigated with a view to revascularisation. Are cardiologists and cardiac surgeons underinvestigating and treating this group of patients or are they properly directing scarce resources away from an intellectually attractive but expensive and high risk management strategy without proved benefit? A number of important questions remain to be answered before revascularisation to improve ventricular function can be considered as a standard treatment strategy for these patients. The prevalence of substantial viable myocardium and ultimately of recoverable left ventricular dysfunction in …
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Pagano et al. (1999) conducted a review in ischaemic heart failure. coronary revascularisation was evaluated. Coronary revascularisation has not been widely adopted for ischaemic heart failure, and important questions remain before it can be considered a standard treatment strategy.
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