Key result
CAD affects ~50% of patients initiating hemodialysis, strongly linked to diabetic nephropathy.
Why the study?
Coronary artery disease prevalence and risk factors at the time of hemodialysis initiation in end-stage renal disease patients were not well characterized.
Observational
Answers are grounded in this paper and cite their sources.
Coronary artery disease is highly prevalent in ESRD patients starting hemodialysis, with a significant proportion having multi-vessel disease, highlighting the need for cardiovascular risk assessment in this population.
= 0.03). Single-, double-, and triple-vessel disease was documented in 17 (38%), 13 (29.5%), and 14 (32.5%) patients, respectively, and the most common vessel involved was the left anterior descending artery. At the initiation of HD in ESRD patients, CAD was seen in almost half of the patients. DN was a significant risk factor for CAD. Other risk factors for CAD include smoking, low cholesterol, low HDL, and high hs-CRP levels.
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Raju et al. (2018) conducted an observational in End-stage renal disease (ESRD) at hemodialysis initiation. Risk factors (Diabetic nephropathy, smoking, low cholesterol, low HDL, high hs-CRP) vs. Absence of risk factors was evaluated on Presence and severity of coronary artery disease (CAD). At the initiation of hemodialysis in end-stage renal disease patients, coronary artery disease was present in almost half of the patients, with diabetic nephropathy being a significant risk factor.
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