Key result
Inflammation remains a key but poorly defined hypothesized driver of AF pathogenesis and perpetuation.
Why the study?
The link between inflammation and atrial fibrillation is still poorly defined and several issues remain unresolved regarding their pathophysiologic relationship and therapeutic targeting.
Population
Patients with or at risk for atrial fibrillation
Comparison
Therapeutic means targeting inflammatory pathways
Design
Review
Authors
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AF inflammation link hypothesized but poorly defined; leaves open validation of therapeutic targets in prospective studies.
This review highlights the pathophysiological link between inflammation and atrial fibrillation, summarizing evidence for the inflammatory hypothesis and potential therapeutic targets.
Γιαννόπουλος et al. (2014) conducted a review in Atrial fibrillation. Inflammation was evaluated. Inflammation is hypothesized to play a key role in the pathogenesis and perpetuation of atrial fibrillation, though the exact link remains poorly defined.
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