Key result
Prednisolone improves symptoms with no 3-month mass recurrence in a Kimura's disease case.
Why the study?
Kimura's disease is a rare immune-mediated chronic inflammatory disorder not previously reported isolated to the post cricoid region.
Case Report (n=1)
This case report highlights a rare presentation of Kimura's disease isolated to the post cricoid region, successfully treated with prednisolone.
Answers are grounded in this paper and cite their sources.
First reported isolated post-cricoid Kimura’s disease; extends anatomic spectrum and leaves open need for site-specific evaluation in eosinophilic disorders.
Kimura’s disease (KD) is a rare immune mediated chronic inflammatory disorder of unknown etiology which involves subcutaneous plane and is usually seen in parotid region. It is also known to affect cervical lymph nodes and pharynx. There has been no report of this disease isolated to post cricoid region. We report a case of hoarseness of voice in an elderly lady who was found to have a smooth mass in post cricoid region with forward displacement and fixity of right arytenoid. She had eosinophilia and biopsy revealed lymphoid hyperplasia with infiltration of eosinophils and vascular proliferation, suggestive of Kimura’s disease. Diagnosis was confirmed by immunohistochemistry. She was treated with prednisolone at a dose of 1 mg per kg body weight per day for 3 weeks. Patient is symptomatically better and mass has not recurred after a period of 3 months.
No takes yet. Share an insight, caveat, or question.
Karunasagar et al. (2017) conducted a case report in Kimura's disease (n=1). Prednisolone was evaluated on Symptom improvement and mass recurrence. Prednisolone treatment in an elderly woman with Kimura's disease of the post cricoid region resulted in symptomatic improvement and no mass recurrence at 3 months.
Synapse has enriched 10 related papers. Consider them for comparative context: