Key result
Long-term risperidone use linked to DVT in a single schizophrenia case report.
Why the study?
There is an increasing number of deep vein thrombosis cases associated with the use of atypical antipsychotics, but detailed reports are limited.
Does long-term use of risperidone induce deep vein thrombosis in patients with schizophrenia?
Case Report (n=1)
Does long-term use of risperidone induce deep vein thrombosis in patients with schizophrenia?
This case report highlights the potential risk of deep vein thrombosis associated with long-term use of atypical antipsychotics such as risperidone, emphasizing the need for psychiatric vigilance.
Long-term risperidone may associate with late DVT in schizophrenia; Level 5 evidence leaves open causality and requires prospective confirmation.
There are increasing number of deep vein thrombosis (DVT) cases that are associated with the use of atypical antipsychotics. We are presenting a case report of a female patient who suffered from DVT. She was a known case of schizophrenia and was on risperidone 4 mg for the last 5 years. She had good physical health before that and there were no known risk factors for DVT. The family history of DVT was also found to be negative. She was managed by intravenous heparin followed by oral warfarin and amisulpride 100 mg/day. Atypical antipsychotics can induce DVT, and psychiatrist should be careful about it.
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Nijhawan et al. (2016) conducted a case report in Schizophrenia and Deep Vein Thrombosis (n=1). Risperidone was evaluated on Deep vein thrombosis. Long-term use of risperidone (4 mg for 5 years) was associated with the development of deep vein thrombosis in a female patient with schizophrenia.
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