The distribution of adenovirus antibodies in normal children

The levels of neutralizing antibody against several adenovirus serotypes were determined on 42 paired specimens of maternal and cord serum and on 197 single serum specimens from children up to the age of 8 years. The antibody distribution indicates that adenovirus infection is endemic in Sheffield just as it has been shown to be endemic in Cleveland and Washington. We should like to thank Prof. C. P. Beattie for his advice and criticism, Dr C. C. Bowley of the Sheffield Regional Blood Transfusion Centre for paired maternal and cord sera, Dr M. H. Hambling for the provision of adenovirus stock strains and Mr Foster, medical artist, for preparation of the figures.