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February 13, 2019CureusOpen Access

Spontaneous Coronary Artery Dissection in a Patient with Undiagnosed Ehlers-Danlos Syndrome

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Key result

Conservative DAPT and statin therapy successfully manages SCAD in a patient with undiagnosed EDS.

  • n=1

Why the study?

Spontaneous coronary artery dissection is a rare and often misdiagnosed cause of acute myocardial infarction with high in-hospital mortality, requiring increased awareness especially in patients with underlying connective tissue disorders.

Design

Case report

Follow-up

Strict follow-up after discharge

Authors

ZNZeid NesheiwatMMMuhammad Asif MangiDKDaniel Kosinski

Discussion

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Member takes

Overview

May support conservative management in SCAD with EDS; hypothesis-generating and requires prospective validation before practice change.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 38-year-old female with previously undiagnosed Ehlers-Danlos Syndrome who presented with spontaneous coronary artery dissection.
I
Intervention
Medical treatment with dual antiplatelet therapy and statin.
O
Outcome
Clinical course and discharge status.

This case highlights the importance of evaluating for underlying connective tissue disorders such as Ehlers-Danlos Syndrome in young, otherwise healthy patients presenting with spontaneous coronary artery dissection.

Limitations

  • Single case report

Cite This Study

Nesheiwat et al. (2019) conducted a case report in Spontaneous Coronary Artery Dissection (n=1). Conservative medical management (dual antiplatelet therapy and statin) was evaluated. Conservative medical management with dual antiplatelet therapy and a statin was successfully used to treat a 38-year-old female with spontaneous coronary artery dissection and undiagnosed Ehlers-Danlos Syndrome.

synapsesocial.com/papers/6aaf9a6ddfdb3477795d2f1bhttps://doi.org/10.7759/cureus.4065
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