Key result
Older age linked to ~5% higher symptomatic CHD risk in adults with Moyamoya disease.
Why the study?
The prevalence and characteristics of symptomatic coronary heart disease in patients with moyamoya disease were not well defined.
Population
456 patients examined for moyamoya disease between 1995 and 2012
Comparison
Patients with symptomatic CHD vs without CHD among MMD patients
Design
Retrospective observational study
Authors
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May warrant age-focused CHD vigilance in MMD; leaves open whether screening improves outcomes.
Observational (n=456)
No
Odds Ratio: 1.053 (95% CI 1.008–1.11)
p-value: p=0.021
Symptomatic coronary heart disease is present in 4.6% of patients with moyamoya disease and may represent a systemic manifestation of the disease despite low traditional risk scores.
Nam et al. (2015) conducted an observational in Moyamoya disease (n=456). Age (per 1 year increase) was evaluated on Symptomatic coronary heart disease (CHD) (OR 1.053, 95% CI 1.008-1.110, p=0.021). Among adult patients with Moyamoya disease, the prevalence of symptomatic coronary heart disease was 4.6%, and older age was significantly associated with its occurrence (OR 1.053).
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