Von Willebrand factor, paravalvular leak, and a new vista for TAVR
Key result
Persistent aortic regurgitation after TAVR is associated with a continued coagulation defect due to degradation of von Willebrand Factor, offering potential diagnostic utility for paravalvular leak.
Design
Editorial
Authors
Discussion
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Member takes
Implication
Highlights the diagnostic potential of monitoring von Willebrand factor levels to detect and assess paravalvular leak following transcatheter aortic valve replacement.
PICO
P
Population
Aortic stenosis and paravalvular leak
I
Intervention / Comparator
Transcatheter aortic valve replacement (TAVR)
Highlights the diagnostic potential of monitoring von Willebrand factor levels to detect and assess paravalvular leak following transcatheter aortic valve replacement.
Cite This Study
Kleiman et al. (2016) conducted an editorial in Aortic stenosis and paravalvular leak. Transcatheter aortic valve replacement (TAVR) was evaluated. Persistent aortic regurgitation after TAVR is associated with a continued coagulation defect due to degradation of von Willebrand Factor, offering potential diagnostic utility for paravalvular leak.