Key result
3D TTE measures maximum ASD diameters ~0.34 cm larger than 2D TOE with comparable closure suitability.
Why the study?
The usefulness of three-dimensional transthoracic echocardiography in assessing secundum ASDs for device closure compared to two-dimensional TOE was uncertain.
Does 3D transthoracic echocardiography provide comparable data to 2D transesophageal echocardiography for assessing secundum ASDs prior to device closure?
Observational (n=24)
Does 3D transthoracic echocardiography provide comparable data to 2D transesophageal echocardiography for assessing secundum ASDs prior to device closure?
Mean Difference: 0.34
p-value: p=<0.001
3D transthoracic echocardiography provides comparable data to 2D transesophageal echocardiography for assessing ASD suitability for device closure, potentially avoiding the need for sedation.
3D TTE may support ASD suitability assessment comparably to TEE; leaves open whether it can safely reduce TEE use pending prospective validation.
AIMS: To determine the usefulness of three-dimensional transthoracic echocardiography (3D echo) in assessment of secundum atrial septal defects (ASDs) considered for device closure. To compare the findings from 3D echo with those from two-dimensional transoesophageal echocardiography (TOE) regarding dimensions, morphology and suitability for device closure. METHODS AND RESULTS: Twenty-four patients were enrolled in this prospective, crossover study. Three-dimensional echo and TOE data were collected, analysed and compared, assessing quantitative data including maximum defect diameter, area and circumference. Qualitative morphology such as the presence of fenestrations and the defect margins were noted, and an assessment of the suitability for device closure was made using each modality. Eighteen (75%) of the 3D data sets produced usable data for analysis. In each case the maximum diameter of the defect was larger on 3D echo than on TOE (mean difference = 0.34 cm, P < 0.001). On three occasions suitability for device closure could not be determined using 3D echo. On the other 15 occasions there was agreement between the TOE and 3D echo data. CONCLUSIONS: Three-dimensional echo provides comparable data with TOE when attempting to predict suitability for device closure without the need for general anaesthetic or sedation. It also provides useful additional dynamic and morphological information.
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Morgan et al. (2007) conducted an observational in Secundum atrial septal defects (ASDs) (n=24). Three-dimensional transthoracic echocardiography (3D echo) vs. Two-dimensional transoesophageal echocardiography (TOE) was evaluated on Maximum defect diameter (Mean difference 0.34 cm, p=<0.001). Three-dimensional transthoracic echocardiography measured larger maximum ASD diameters than 2D transoesophageal echocardiography (mean difference 0.34 cm, P<0.001) with comparable suitability data.
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