Key result
CTO DES implantation is linked to a ~9% reduction in end-systolic volume index.
Why the study?
The effect of recanalization of chronic total coronary occlusion on long-term left ventricular function and the value of myocardial viability assessment with MRI is incompletely understood.
Does successful drug-eluting stent implantation for chronic total coronary occlusion improve left ventricular volumes and function, and can this be predicted by pre-procedural MRI?
Population
27 patients with chronic total coronary occlusion
Comparison
Left ventricular function before and after drug-eluting stent implantation
Design
Observational cohort study with contrast-enhanced MRI
Follow-up
5 months
Authors
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Successful drug-eluting stent implantation for CTO significantly improves left ventricular volumes, and this improvement correlates with the extent of dysfunctional but viable myocardium assessed by pre-procedural MRI.
Observational (n=27)
Does successful drug-eluting stent implantation for chronic total coronary occlusion improve left ventricular volumes and function, and can this be predicted by pre-procedural MRI?
Absolute Event Rate: 31% vs 34%
p-value: p=0.02
Successful drug-eluting stent implantation for CTO significantly improves left ventricular volumes, and this improvement correlates with the extent of dysfunctional but viable myocardium assessed by pre-procedural MRI.
Baks et al. (2006) conducted an observational in Chronic total coronary occlusion (n=27). Drug-eluting stent implantation vs. Baseline (before revascularization) was evaluated on Mean end-systolic volume index (p=0.02). Drug-eluting stent implantation for chronic total occlusion reduced mean end-systolic volume index from 34 to 31 ml/m2 (p=0.02) and end-diastolic volume index from 84 to 79 ml/m2 (p<0.002).
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