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January 1, 1997Journal of the American Society of EchocardiographyOpen Access

Optimal number of beats for the Doppler measurement of cardiac output in atrial fibrillation

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Key result

AF requires ~3 times more beats than SR to reliably estimate cardiac output.

  • n=33

Why the study?

The optimum number of Doppler velocity waveforms required to accurately calculate cardiac output in atrial fibrillation compared to sinus rhythm was unknown.

Does the number of Doppler velocity waveforms required to accurately calculate cardiac output differ between patients in atrial fibrillation and those in sinus rhythm?

Comparison

Cardiac output calculation in atrial fibrillation vs sinus rhythm

Design

Observational study

Authors

SDSimon W DubreyGeneral CardiologyRFRodney H. FalkHeart Failure & Transplant

Discussion

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Implication

Averaging ~13 beats may limit CO variability to <2% in AF; leaves open whether this protocol improves routine echocardiographic accuracy.

Study Design

Type

Observational (n=33)

Structured PICO

Does the number of Doppler velocity waveforms required to accurately calculate cardiac output differ between patients in atrial fibrillation and those in sinus rhythm?

P
Population
33 subjects (21 with atrial fibrillation and 12 controls in sinus rhythm) undergoing Doppler measurement of cardiac output.
E
Exposure
Calculation of cardiac output derived from aortic Doppler waveform velocity time integrals and RR intervals.
C
Comparator
Control group of 12 subjects in sinus rhythm.
O
Outcome
Optimum number of Doppler velocity waveforms required to calculate cardiac output with a variability of less than 2%.surrogate

Main Result

Absolute Event Rate: 13% vs 4%

Accurate Doppler measurement of cardiac output in atrial fibrillation requires averaging approximately 13 beats, which is three times the number needed in sinus rhythm.

Cite This Study

Dubrey et al. (1997) conducted an observational in Atrial fibrillation (n=33). Atrial fibrillation vs. Sinus rhythm was evaluated on Number of beats required to achieve an estimation of cardiac output with a variability of less than 2%. Atrial fibrillation required a mean of 13 beats to estimate cardiac output with <2% variability, compared with a mean of 4 beats in sinus rhythm.

synapsesocial.com/papers/6ab07a6fbdc4c78995d3af17https://doi.org/10.1016/s0894-7317(97)80034-x

Topics

Atrial fibrillationPersistent AF managementAnticoagulation in AF
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Postextrasystolic potentiation and its contribution to the beat-to-beat variation of the pulse during atrial fibrillation.1992 · 63 citations
  2. 2Study of Ventricular Response in Atrial Fibrillation1961 · 59 citations
  3. 3Effect of increasing heart rate on Doppler indices of left ventricular performance in healthy men1992 · 41 citations
  4. 4Analysis of R-R Intervals in Patients with Atrial Fibrillation at Rest and During Exercise1970 · 140 citations
  5. 5Intraoperative detection of myocardial ischemia in high-risk patients: electrocardiography versus two-dimensional transesophageal echocardiography.1985 · 466 citations