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Electrical field stimulation of the small intestine in vivo in cats induces a 60–150% increase in total intestinal blood flow. The vasodilatory response to field stimulation is blocked by tetrodotoxin and lidocaine, but is unaffected by extrinsic denervation of the intestine, by cholinergic and adrenergic pharmacological blocking agents, and also by cross perfusion of the stimulated intestine from a donor animal. The participation of a local nervous structure in the control of intestinal blood flow is suggested.
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Biber et al. (1973) studied this question.
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