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August 31, 2009Catheterization and Cardiovascular Interventions

First trans‐axillary implantation of Edwards Sapien valve to treat an incompetent aortic bioprosthesis

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Key result

Trans-axillary TAVR proves feasible for a severely regurgitant aortic bioprosthesis with a functioning LIMA graft.

  • n=1

Why the study?

There are case reports of transcatheter aortic valves to treat dysfunctional aortic bioprostheses and case series of transaxillary CoreValve implantation, but no prior report of Edwards Sapien valve via transaxillary approach.

Comparison

Edwards Sapien 23 mm transcatheter valve implantation via left axillary artery

Design

Case report

Authors

ASAndrew S.P. SharpUniversity College DublinIMIassen MichevInterventional / Structural CardiologyAntonio ColomboAntonio ColomboInterventional / Structural Cardiology

Discussion

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Implication

May expand access options for valve-in-valve TAVR; extends limited case experience but leaves open broader safety questions.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
1 patient with a functioning LIMA graft and a severely regurgitant Freestyle 23 mm aortic bioprosthesis.
I
Intervention
Implantation of an Edwards Sapien 23 mm transcatheter aortic valve through the left axillary artery
O
Outcome
Successful implantation

This case report demonstrates the feasibility of trans-axillary implantation of an Edwards Sapien valve for treating a dysfunctional aortic bioprosthesis in a patient with a functioning LIMA graft.

Cite This Study

Sharp et al. (2009) conducted a case report in Severely regurgitant aortic bioprosthesis (n=1). Edwards Sapien transcatheter aortic valve implantation through the left axillary artery was evaluated on Successful implantation. Trans-axillary implantation of an Edwards Sapien 23 mm transcatheter aortic valve was successfully performed in a patient with a severely regurgitant aortic bioprosthesis and functioning LIMA graft.

synapsesocial.com/papers/6ab07b93d764775e82efa8b8https://doi.org/10.1002/ccd.22254
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transapical Transcatheter Aortic Valve Implantation in Humans2006 · 567 citations
  2. 2First Successful Aortic Valve Implantation with the CoreValve ReValving™ System via Right Subclavian Artery Access: A Case Report2008 · 110 citations
  3. 3Percutaneous Aortic Valve Implantation Retrograde From the Femoral Artery2006 · 905 citations
  4. 4Transapical Minimally Invasive Aortic Valve Implantation2007 · 620 citations
  5. 5Transcatheter valve implantation for patients with aortic stenosis: a position statement from the European Association of Cardio-Thoracic Surgery (EACTS) and the European Society of Cardiology (ESC), in collaboration with the European Association of Percutaneous Cardiovascular Interventions (EAPCI)2008 · 723 citations