Key result
Chemotherapy fails to prevent rapid death in a man with primary pulmonary peripheral T-cell lymphoma.
Why the study?
Primary pulmonary T-cell lymphoma is a rare disease with poor prognosis that requires early distinction and diagnosis.
Case Report (n=1)
Primary pulmonary peripheral T-cell lymphoma is a rare condition with a poor prognosis that can progress rapidly despite chemotherapy.
Rapid progression despite chemotherapy in this rare lymphoma warrants clinical vigilance; leaves open need for effective therapies.
Primary pulmonary T-cell lymphoma is a rare condition characterized by fever, cough, dyspnea, and bilateral pulmonary nodules, usually diagnosed by transbronchial biopsy or computed tomography (CT) guided needle biopsy and pathology. In view of its poor prognosis, it is critical to distinguish and diagnose this disease as early as possible. We report here a case of a 39-year-old man who presented with fever, cough, expectoration with multiple nodules, and patch shadow in both lungs by chest CT. Tissue samples were taken by CT guided needle biopsy. The histological sample and immunohistochemistry showed peripheral T-cell lymphoma-not otherwise specified (PTCL-NOS). After the patient was treated by chemotherapy for two courses, his condition deteriorated rapidly and he died 2.3 months after the onset of the disease.
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Zhang et al. (2013) conducted a case report in Primary pulmonary peripheral T-cell lymphoma (n=1). Chemotherapy was evaluated on Clinical course and survival. A 39-year-old man with primary pulmonary peripheral T-cell lymphoma treated with two courses of chemotherapy deteriorated rapidly and died 2.3 months after disease onset.
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