Key result
Chemotherapy with cyclophosphamide, vincristine, and prednisone resulted in complete remission of symptoms and no disease progression during a 4-year follow-up in a patient with primary pulmonary MALT lymphoma.
Case Report (n=1)
No
Primary pulmonary mucosa-associated lymphoid tissue lymphoma is a rare neoplasm with an indolent course and favorable prognosis following chemotherapy.
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May support CVP for symptom control in primary pulmonary MALT lymphoma; hypothesis-generating and requires prospective validation.
Primary pulmonary non-Hodgkin's lymphoma is a very rare neoplasm. It is most frequently represented by the mucosa-associated lymphoid tissue type. We describe a case of a 67-year-old woman who presented with fatigue, mild dyspnea, and consolidation on chest radiograph. The diagnosis of non-Hodgkin's lymphoma was established by transbronchial biopsy, and chemotherapy was then started. The patient was treated with 6 cycles of chemotherapy. She had good response to therapy and no progression of the disease was observed during a 4-year follow-up period. The clinical, radiological and histopathological features are described. This entity has an indolent course, good response to therapy and favorable prognosis. However, despite being an incidental radiological finding in a third of cases, this disease remains highly underdiagnosed.
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Santos et al. (2009) conducted a case report in Primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma (n=1). Chemotherapy (cyclophosphamide, vincristine, prednisone) was evaluated on Disease remission and progression. Chemotherapy with cyclophosphamide, vincristine, and prednisone resulted in complete remission of symptoms and no disease progression during a 4-year follow-up in a patient with primary pulmonary MALT lymphoma.
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