Key result
LAPWI shows no benefit over PVRI alone for 1-year freedom from atrial arrhythmias off AADs.
Why the study?
It remains unclear whether additional left atrial posterior wall isolation beyond pulmonary vein reisolation benefits atrial fibrillation patients undergoing repeat ablation.
Does left atrial posterior wall isolation improve freedom from atrial arrhythmias in patients with atrial fibrillation undergoing repeat ablation?
Cohort (n=196)
Does left atrial posterior wall isolation improve freedom from atrial arrhythmias in patients with atrial fibrillation undergoing repeat ablation?
Absolute Event Rate: 43.7% vs 69.9%
p-value: p=.50
In patients undergoing repeat ablation for atrial fibrillation, additional left atrial posterior wall isolation did not improve 1-year freedom from atrial arrhythmias compared to pulmonary vein reisolation alone.
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LAPWI addition showed no arrhythmia benefit in this repeat ablation cohort; leaves open its value in persistent AF subgroups for prospective trials.
Pothineni et al. (2021) conducted a cohort in Atrial fibrillation (n=196). Left atrial posterior wall isolation (LAPWI) vs. Pulmonary vein reisolation (PVRI) only was evaluated on Freedom from atrial arrhythmias (AA) off antiarrhythmic drugs (AADs) at 1 year follow-up (p=.50). Left atrial posterior wall isolation did not improve freedom from atrial arrhythmias off antiarrhythmic drugs at 1 year compared to pulmonary vein reisolation alone (43.7% vs 69.9%, P=0.50).
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