Key result
Carotid artery stenting yields an ~8% MACE rate over nearly two years.
Why the study?
Evaluation of complications after carotid artery stenting is essential for proper clinical decision-making in carotid artery stenosis treatment.
What is the rate of major adverse cardiac events and restenosis following carotid artery stenting in patients with significant carotid stenosis?
Observational (n=50)
No
What is the rate of major adverse cardiac events and restenosis following carotid artery stenting in patients with significant carotid stenosis?
Carotid artery stenting in this Iranian cohort demonstrated an 8% rate of composite death, stroke, and MI, and an 8% restenosis rate, which the authors consider comparable to other studies.
BACKGROUND: Carotid artery stenting (CAS) is considered as a safe and effective procedure for treatment of carotid artery stenosis. Evaluation of this procedure's complications is essential for proper clinical decision-making. OBJECTIVE: This study aimed to evaluate the cardiovascular events after CAS among our patients in Isfahan, Iran. METHODS: This case-series study was conducted on fifty patients from December 2013 to May 2016. These patients were referred to the cardiology centers of Isfahan, Iran by a neurologist, for stenting of extracranial carotid arteries. The second step was examining the patients by cardiac interventionist. Stenting was performed on symptomatic patients with carotid artery stenosis of more than 50 percent or asymptomatic patients with more than 70 percent carotid artery stenosis on Doppler ultrasonography. Neurologic evaluation was performed at baseline, during hospital stay, and follow-up. Transient ischemic attack (TIA)/Stroke and Myocardial infarction (MI) questionnaires were filled out by a cardiologist over telephone interviews with the patients, for follow-up of one month, six months and at the end of study. Carotid Doppler ultrasonography was performed before and 6 months after stenting for evaluation of restenosis. Indeed, during the follow-up study, the major adverse cardiac events (MACE) were evaluated. All data were analyzed through SPSS v.17. RESULTS: The mean age of patients was 70.73 (±14.01) years old (range: 48-89 years old). Composite endpoint of death, stroke, and MI was totally 8 percent. The rate of carotid arterial restenosis (Luminal arterial narrowing>50%) was 8%. CONCLUSIONS: Despite the fact that carotid stenting is new in our center, our results can be compared to other important studies.
No takes yet. Share an insight, caveat, or question.
Khosravi et al. (2018) conducted an observational in Carotid artery stenosis (n=50). Carotid artery stenting was evaluated on Composite of death, stroke, and myocardial infarction (MACE). Carotid artery stenting in patients with carotid artery stenosis resulted in an 8% rate of major adverse cardiac events (death, stroke, and myocardial infarction) over a mean follow-up of 674 days.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: