Electrolytic Partial Fluorination of Organic Compounds. 24.1 Highly Regioselective Anodic Monofluorination of 2-Benzothiazolyl and 5-Chloro-2-benzothiazolyl Sulfides

Electrochemical fluorination of 2-benzothiazolyl and 5-chloro-2-benzothiazolyl sulfides was successfully carried out using Et 4 NF·3HF as a supporting electrolyte and fluoride ion source in dimethoxyethane to provide the corresponding α-monofluorinated sulfides in good yields. Fluorination took place selectively at the position α to the sulfur atom of the sulfides, and the heterocyclic moieties were not fluorinated at all.