In India, almost 95% of the prescriptions were plant based in the traditional systems of Unani, Ayurveda, Homeopathy and Siddha.The study of plants continues principally for the discovery of novel secondary metabolites.Around 80% of products were of plant origin and their sales exceeded US $65 billion in 2003 [1].Since ancient times, people have been exploring the nature particularly plants in search of new drugs.This has resulted in the use of large number of medicinal plants with curative properties to treat various diseases.Many higher plants are major sources of natural products used as pharmaceuticals, agrochemicals, flavor and fragrance ingredients, food additives, and pesticides [2].The search for new plant derived chemicals should thus be a priority in current and future efforts toward sustainable conservation and rational utilization of biodiversity [3].In the search for alternatives to production of desirable medicinal compounds from plants, biotechnological approaches, specifically, plant tissue cultures, are found to have potential as a supplement to traditional agriculture in the industrial production of bioactive plant metabolites [4].Cell suspension culture systems could be used for large scale culturing of plant cells from which secondary metabolites could be extracted.The advantage of this method is that it can ultimately provide a continuous, reliable source of natural products.The soil physiochemical and trace metal concentrations may alter the physiology of the living things [5][6][7][8].The secondary metabolites from the biological things are very essential for pharmaceutical applications and some of the strains are resistant to drugs [9].
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John et al. (2015) studied this question.
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